What is the efficacy of combined doxycycline and streptomycin for the treatment of brucellosis?

Updated: Apr 22, 2021
  • Author: Nicholas John Bennett, MBBCh, PhD, FAAP, MA(Cantab); Chief Editor: Michael Stuart Bronze, MD  more...
  • Print

A 2012 Cochrane review found that a regimen consisting of doxycycline for 6 weeks plus streptomycin for 2-3 weeks was more effective than one consisting of doxycycline plus rifampicin for 6 weeks. [59] The investigators also found that a regimen consisting of a fluoroquinolone plus rifampicin for 6 weeks was as effective overall as doxycycline plus rifampin (though the evidence for this conclusion was of low quality) and was slightly better tolerated.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!