What is the role of lab testing in the diagnosis of bartonellosis (Bartonella infection)-related catscratch disease?

Updated: Jun 19, 2019
  • Author: Kassem A Hammoud, MD; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Answer

Laboratory studies include the following:

  • Diagnosis should be confirmed with demonstration of a 4-fold rise in antibody levels, initially immunoglobulin M (IgM) followed by immunoglobulin G (IgG).

  • Culture confirmation is difficult; PCR is more sensitive. [25]

  • In some patients, hypercalcemia complicates catscratch disease lymphadenopathy via overproduction of vitamin D due to granuloma formation.


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