What are the Infectious Diseases Society of America (IDSA) guidelines on the management of babesiosis?

Updated: Apr 01, 2021
  • Author: Rachel E Strength, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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The IDSA recommends treating babesiosis with the combination of atovaquone plus azithromycin or the combination of clindamycin plus quinine.

The IDSA suggests exchange transfusion using red blood cells in selected patients with severe babesiosis.

The IDSA recommends monitoring Babesia parasitemia during treatment of acute illness in immunocompetent patients using peripheral blood smears. The IDSA recommends against testing for parasitemia once symptoms are resolved.

The IDSA suggests monitoring Babesia parasitemia in immunocompromised patients using peripheral blood smears even after patients become asymptomatic and until blood smears are negative. The IDSA suggests PCR testing be considered if blood smears become negative but symptoms persist.

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