When is exchange transfusion indicated in the treatment of babesiosis?

Updated: Apr 01, 2021
  • Author: Rachel E Strength, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Exchange transfusion is employed in patients who are profoundly ill with high levels of parasitemia and hemolysis. In severe cases of babesiosis—as demonstrated by high parasitemia (>10%), significant hemolysis, or renal, hepatic, or pulmonary dysfunction—it may be lifesaving. [3] When used concurrently with chemotherapy, exchange transfusion reduces the level of parasitemia and may remove toxic erythrocyte, babesial, or macrophage-produced factors.

 


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