When is an activated partial thromboplastin time (aPTT) test indicated?

Updated: Jul 02, 2021
  • Author: Muhammad Bader Hammami, MD; Chief Editor: Eric B Staros, MD  more...
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aPTT is indicated for the following [1, 2, 6] :

  • Unexplained bleeding or bruising

  • Thrombotic episode or recurrent miscarriages

  • To evaluate the effectiveness of drug therapy (eg, unfractionated heparin therapy)

  • To assess the integrity of the intrinsic and final common pathways

  • As part of a presurgical screen (if the patient has a history of bleeding or easy bruising)

  • As part of an evaluation for lupus anticoagulant or anticardiolipin antibodies

  • As part of coagulation panel workup

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