Which tests are performed in the workup of anaplastic large cell lymphoma (ALCL)?

Updated: May 08, 2020
  • Author: Delong Liu, MD, PhD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Answer

The imaging and laboratory tests that are necessary to evaluate a patient who may have anaplastic large cell lymphoma (ALCL) are similar to those recommended in the standard evaluation of aggressive non-Hodgkin lymphomas.

Testing for breast implant–associated ALCL involves collecting fresh seroma fluid and representative portions of the capsule. Diagnostic evaluation should include cytological evaluation of seroma fluid with Wright-Giemsa–stained smears and cell block immunohistochemistry testing for cluster of differentiation (CD) and anaplastic lymphoma kinase (ALK) markers. [6]


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