What are the treatment regimens for hepatitis C virus (HCV) genotype 3 following prior PEG-IFN and RBV treatment failure?

Updated: Dec 09, 2020
  • Author: David C Wolf, MD, FACP, FACG, AGAF, FAASLD; Chief Editor: Michael Stuart Bronze, MD  more...
  • Print
Answer

Answer

Patients without cirrhosis [28]

  • Daily fixed-dose combination of sofosbuvir (400 mg)/velpatasvir (100 mg) for 12 weeks

Patients with compensated cirrhosis [28]

  • Daily fixed-dose elbasvir (50 mg)/grazoprevir (100 mg) plus sofosbuvir (400 mg) for 12 weeks
  • Daily fixed-dose combination of sofosbuvir (400 mg)/velpatasvir (100 mg)/voxilaprevir (100 mg) for 12 weeks

Patients with sofosbuvir and RBV treatment failures [28]

  • Daily fixed-dose combination of sofosbuvir (400 mg)/velpatasvir (100 mg)/voxilaprevir (100 mg) for 12 weeks
  • Weight-based ribavirin for 12 weeks for individuals with prior NS5A inhibitor failure and cirrhosis

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!