Which medications in the drug class Antineoplastics, Anthracycline are used in the treatment of Waldenstrom Macroglobulinemia?

Updated: Feb 01, 2021
  • Author: Karen Seiter, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Antineoplastics, Anthracycline

These agents immunomodulate the response to malignant cells.

Doxorubicin (Adriamycin)

Doxorubicin inhibits topoisomerase II and produces free radicals, which may cause destruction of DNA. The combination of these 2 events can, in turn, inhibit the growth of neoplastic cells. Doxorubicin may be effective in chlorambucil-refractory Waldenström macroglobulinemia.


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