Which medications in the drug class Antihistamines are used in the treatment of Transfusion Reactions?

Updated: Jan 12, 2021
  • Author: S Gerald Sandler, MD, FCAP, FACP; Chief Editor: Emmanuel C Besa, MD  more...
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Antihistamines prevent histamine response in sensory nerve endings and blood vessels. These agents are more effective in preventing histamine response than in reversing it.

Diphenhydramine hydrochloride (Benadryl, Diphen)

Antihistamine with anticholinergic effects that competes with histamine for receptor sites on effector cells. Among other indications, used to treat urticaria, pruritus, and other histamine-mediated manifestations of allergic reactions to blood products.

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