Which lab studies are performed in the evaluation of febrile nonhemolytic transfusion reactions?

Updated: Jan 12, 2021
  • Author: S Gerald Sandler, MD, FCAP, FACP; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

In febrile nonhemolytic reactions, [57] the recipient's plasma has a normal appearance on visual inspection. Red discoloration indicating hemolysis excludes this diagnosis. The recipient's urine also has a normal appearance. Red discoloration indicating hemolysis excludes this diagnosis. On retyping of donor and recipient red cells for ABO/Rh(D), the results are concordant; no discrepancy should be detected. A direct antiglobulin (Coombs) test yields a negative result.


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