What are physical findings suggestive of acute hemolytic or nonhemolytic transfusion reactions?

Updated: Jan 12, 2021
  • Author: S Gerald Sandler, MD, FCAP, FACP; Chief Editor: Emmanuel C Besa, MD  more...
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Acute hemolytic reactions manifest as follows:

  • Early signs may include fever, hypotension, flushing, wheezing, anxiety, and/or red-colored urine

  • Late signs may include a generalized bleeding tendency (DIC) and/or hypotension

Nonhemolytic febrile reactions typically involve only fever. However, some patients also have severe rigors, shaking, chills, hypotension, and vomiting.

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