What causes a bacterial contamination leading to acute transfusion reactions?

Updated: Jan 12, 2021
  • Author: S Gerald Sandler, MD, FCAP, FACP; Chief Editor: Emmanuel C Besa, MD  more...
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Answer

Bacterial contamination and endotoxemia may result from any of the following:

  • Inadequate sterile preparation of the phlebotomy site
  • Opening the blood container in a nonsterile environment
  • The presence of bacteria in the donor's circulation at the time of blood collection

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