Which medications in the drug class Urologics, Other are used in the treatment of Interstitial Cystitis?

Updated: Dec 04, 2020
  • Author: Eric S Rovner, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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Urologics, Other

Instillation therapy may use dimethyl sulfoxide (DMSO). It may also use cauterizing agents for the removal of granulation tissue and dermatologic agents for their cleansing and disinfection and for the removal of necrotic debris.

Dimethyl sulfoxide (Rimso-50)

Dimethyl sulfoxide (DMSO) provides anti-inflammatory action, membrane penetration, antifungal activity, cryoprotective effects for living cells and tissues, collagen dissolution action, mast cell stimulation, nerve blockade, diuresis, cholinesterase inhibition, vasodilation, and muscle relaxation. It may be combined with heparin, steroids, or bicarbonate. In adults, instill 50mL of aqueous 50% solution directly into the bladder by catheter or Asepto syringe and allow it to remain for 20 minutes. DMSO is a pregnancy category X drug.

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