What are the American Urological Association (AUA) second-line treatment recommendations for interstitial cystitis/bladder pain syndrome (IC/BPS)?

Updated: Dec 04, 2020
  • Author: Eric S Rovner, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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AUA second-line treatment recommentations include the following [3] :

  • Appropriate manual physical therapy techniques should be offered, if trained clinicians are available; however, pelvic floor strengthening exercises (eg, Kegel exercises) should be avoided
  • Multimodal pain management 
  • Amitriptyline, cimetidine, hydroxyzine, or pentosan polysulfate (PPS)
  • Dimethyl sulfoxide (DMSO), heparin, or lidocaine

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