What is the role of urine studies in the diagnosis of interstitial cystitis/bladder pain syndrome (IC/BPS)?

Updated: Dec 04, 2020
  • Author: Eric S Rovner, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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Urinalysis results are usually normal. Microscopic hematuria and pyuria are present in some patients. Much research is being undertaken to identify urine markers expressed in patients with interstitial cystitis to develop a noninvasive laboratory test. By definition, urine culture results should be negative.

The absence of any abnormal urine cytology findings specifically suggests a diagnosis of interstitial cystitis. A voided or catheterized urine specimen demonstrating cytologic changes consistent with dysplasia, carcinoma in situ, or frank cancer should prompt immediate further urologic evaluation.

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