What is the role of biopsy in the diagnosis of interstitial cystitis/bladder pain syndrome (IC/BPS)?

Updated: Dec 04, 2020
  • Author: Eric S Rovner, MD; Chief Editor: Edward David Kim, MD, FACS  more...
  • Print

Some centers advocate limiting the use of cystoscopy and biopsy in the evaluation and workup of patients thought to have interstitial cystitis; however, such a biopsy may be helpful to help exclude other disorders. Biopsies are performed primarily to help rule out other varieties of cystitis or malignant or premalignant (eg, carcinoma in situ) lesions. They are also performed to evaluate for detrusor mastocytosis, which some authors have used in directing therapy (see discussion below). Postoperative catheter drainage should be instituted in patients who undergo deep biopsies to reduce the chance of perforation, extravasation, or both.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!