How is high-risk for HIV infection determined prior to preexposure prophylaxis (PrEP)?

Updated: Oct 08, 2019
  • Author: Alejandro Delgado, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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When considering emtricitabine/tenofovir for PrEP, it is important to identify individuals at high risk. High-risk patients include those who have partner(s) known to be HIV-1 infected or who engage in sexual activity within a high prevalence area or social network and exhibit one or more of the following:

  • Inconsistent or no condom use

  • Diagnosis of sexually transmitted infections

  • Exchange of sex for commodities (eg, money, food, shelter, drugs)

  • Use of illicit drugs or alcohol dependence

  • Incarceration partner(s) of unknown HIV-1 status with any of the factors listed above

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