Which conditions must be differentiated from secondary polycythemia?

Updated: Jul 20, 2020
  • Author: Srikanth Nagalla, MBBS, MS, FACP; Chief Editor: Sara J Grethlein, MD, FACP  more...
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Answer

Secondary polycythemia must be differentiated from primary polycythemia and relative polycythemia (in which RBC numbers are normal but plasma volume is contracted. The reduction in plasma volume may be due to dehydration or to reduced venous compliance; the latter is also termed stress polycythemia or Gaisböck syndrome, and is typically seen in obese middle-aged men who are receiving a diuretic for treatment of hypertension. See Presentation and Workup.


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