What are the instructions for administering insulin with prefilled pens?

Updated: Oct 04, 2017
  • Author: Mini A Mathew, DO, PharmD; Chief Editor: George T Griffing, MD  more...
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Instructions for using prefilled pens are as follows:

  1. Roll the pen between the palms 10 times and invert 180° 10 times

  2. Twist on the needle; a new needle should be used for each administration

  3. Pull off the needle cap; do not discard the outer needle cap

  4. To avoid air and to ensure proper dose, you will need to prime the syringe each time; to do this, dial 2 units; hold the pen with the needle pointing up and tap the cartridge gently a few times to get rid of any air bubble; press the push button all the way in until the dose selector returns to zero; a drop of insulin must appear at the needle tip; if not, change the needle and repeat the procedure

  5. Once the priming is done, check that the dose selector is set at zero

  6. Dial the number of units you need to inject

  7. Select the area; pinch the skin and inject into the skin; you should hear a confirmatory click

  8. After injecting, the needle should remain in the skin for at least 6 seconds

  9. Put outer cap back onto the needle, unscrew the needle, and dispose of it properly

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