Which disorders are associated with hemothorax?

Updated: Jul 13, 2020
  • Author: Mary C Mancini, MD, PhD, MMM; Chief Editor: Jeffrey C Milliken, MD  more...
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Case reports involve associated disorders such as hemorrhagic disease of the newborn (eg, vitamin K deficiency), Henoch-Schönlein purpura, and beta thalassemia/hemoglobin E disease. [14, 15, 16, 17] Congenital cystic adenomatoid malformations occasionally result in hemothorax. [18] A case of massive spontaneous hemothorax has been reported with Von Recklinghausen disease. [19] Spontaneous internal thoracic artery hemorrhage was reported in a child with type IV Ehlers-Danlos syndrome.

Hemothorax has also been reported in association with costal cartilaginous anomalies. [20, 21, 22, 23] Rib tumors have rarely been reported in association with hemothorax. Intrathoracic rupture of an osteosarcoma of a rib caused hemorrhagic shock in a 13-year-old girl. [24]

Hemothorax has been noted to complicate a small fraction of spontaneous pneumothorax cases. Although rare, it is more likely to occur in young adolescent males and can be life-threatening secondary to massive bleeding. [25]

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