What is included in intrapartum antiretroviral therapy (ART) for pregnant women with HIV infection?

Updated: Jul 26, 2021
  • Author: Madhu Chhanda Choudhary, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Answer

Intrapartum AZT should be administered to pregnant HIV-infected women if the HIV viral load is 1000 or more copies/mL or unknown at time of delivery, irrespective of mode of delivery. [24]  If HIV viral load is between 50 to 1000 copies/ml at 34-36 weeks of pregnancy or 4-6 weeks before delivery, intrapartum AZT may be considered.

AZT 2 mg/kg IV is administered over 1 hour, then continuous infusion of 1 mg/kg/h from onset of labor to delivery.

Oral AZT, if part of the combination regimen, should be stopped while IV AZT is administered.


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