Which clinical history findings are characteristic of follicular lymphoma?

Updated: Mar 03, 2020
  • Author: Lauren C Pinter-Brown, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Follicular lymphoma most commonly presents as a painless, slowly progressive adenopathy. Some patients have waxing and waning adenopathy.

Systemic symptoms, such as fever, drenching night sweats, and/or weight loss in excess of 10% of ideal body weight, are infrequent at presentation but can be observed in later stages of the disease. Transformation to an intermediate-grade or high-grade lymphoma should be considered when a patient develops systemic symptoms or rapid enlargement of a lymph node.

Symptoms related to bone marrow dysfunction, such as anemia, leukopenia, or thrombocytopenia, are rare at presentation but can also be observed in the later stages of the disease.

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