What is the prevalence of follicular lymphoma?

Updated: Mar 03, 2020
  • Author: Lauren C Pinter-Brown, MD; Chief Editor: Emmanuel C Besa, MD  more...
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Non-Hodgkin lymphoma (NHL) is the fifth most frequently diagnosed malignancy in the United States. The American Cancer Society estimates that 77,240 cases of non-Hodgkin lymphoma will be diagnosed in 2020. [1] Follicular lymphomas constitute approximately 20% of NHLs. [2] No sex preponderance is seen.

In general, age-adjusted incidence rates of NHL are higher in more developed countries. The incidence of follicular lymphomas increases with age; these conditions are extremely rare in children, though the World Health Organization has delineated a pediatric variant. The median age at diagnosis is 60-65 years. The age-adjusted incidence rates of NHL varied from 3.7-14 cases per 100,000 person years from 1983-1987 in different countries.

Variations in racial incidence are found throughout the world. The incidence of follicular lymphomas is low in China and Japan, but people of Ashkenazi Jewish ancestry have a higher incidence of lymphoma. In the United States, the incidence is 2-3 times higher in whites than in blacks. [15]

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