Which factors may reduce the mortality rate for Fournier gangrene?

Updated: Jun 03, 2021
  • Author: Vernon M Pais, Jr, MD; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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Answer

Interestingly, obesity is independently associated with reduced in-hospital mortality in patients with severe soft tissue infections (SSTIs) regardless of the obesity classification, according to a review of 2868 patients with SSTIs, which found that obese patients were less likely to die in hospital than nonobese patients (odds ratio = 0.42, 95% confidence index, 0.25 to 0.7, P=0.001). [55]

Surprisingly, diabetes and HIV infection are not associated with higher mortality. In some studies, Fournier gangrene that originates from anorectal diseases carries a worse prognosis than cases caused by other factors.


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