What are the immunophenotypes of unclassifiable myelodysplastic syndromes (MDS-U)?

Updated: Jul 21, 2020
  • Author: Robert P Hasserjian, MD; Chief Editor: Christine G Roth, MD  more...
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No specific immunophenotype of unclassifiable myelodysplastic syndromes (MDS-U) exists. However, in cases with a hemodilute aspirate but with 1% peripheral blood blasts, CD34 staining of the bone marrow trephine biopsy may help disclose increased and/or clustered blasts. [11] If blasts appear to comprise at least 5% of the bone marrow biopsy cells by this method, a diagnosis of represent myelodysplastic syndrome (MDS) with excess blasts may be suggested rather than MDS-U.

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