What are the preferred single-agent anthracycline regimens for the treatment of recurrent or metastatic breast cancer?

Updated: Apr 23, 2020
  • Author: Joseph A Sparano, MD; Chief Editor: John V Kiluk, MD, FACS  more...
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Answer

Answer

Regimens are as follows:

  • Doxorubicin 60-75 mg/m 2 on day 1 every 3 wk or  20 mg/m 2 IV weekly or
  • Epirubicin 60-90 mg/m 2 IV on day 1 every 3 wk or
  • Pegylated liposomal-encapsulated doxorubicin 50 mg/m 2 IV on day 1 every 4 wk

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