What is included in supportive care for patients undergoing the hyper-CVAD regimen for acute lymphoblastic leukemia (ALL)?

Updated: Jul 02, 2021
  • Author: Karen Seiter, MD; Chief Editor: Matthew C Foster, MD  more...
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Supportive care during hyper-CVAD:

  • Ciprofloxacin 500 mg PO BID (or levofloxacin 500 mg po daily) plus  fluconazole 200 mg PO daily (or alternative azole) plus  acyclovir 200 mg PO BID (or valacyclovir 500 po daily) plus  filgrastim 10 µg/kg SC daily, starting on day 5 of hyper-CVAD and on day 4 of high-dose methotrexate and cytarabine [5]

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