Which medications are used in first-line outpatient pyelonephritis empiric therapy?

Updated: Nov 04, 2020
  • Author: Mony Fraer, MD, MHCDS, FACP, FASN; Chief Editor: Thomas E Herchline, MD  more...
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First-line empiric therapy is with one of the fluoroquinolones listed below:

  • Ciprofloxacin (Cipro) 500 mg PO q12h for 7d
  • Ciprofloxacin extended-release (Cipro XR, Proquin XR) 1000 mg PO q24h for 7d
  • Levofloxacin (Levaquin) 750 mg PO q24h for 5d

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