What are treatment protocols for non-muscle invasive bladder cancer?

Updated: Feb 23, 2021
  • Author: Gary David Steinberg, MD, FACS; Chief Editor: E Jason Abel, MD  more...
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Answer

Answer

Non-muscle invasive bladder cancers are divided into 3 groups: Ta, Tis, and T1:

  • Ta are noninvasive papillary lesions confined to the urothelium and have not penetrated the basement membrane
  • Tis tumors are defined as severe cellular dysplasias usually in the absence of tumor formation
  • T1 tumors are invasive cancers that have penetrated into underlying lamina propria but without any involvement of the muscularis propria

Standard treatment for non-muscle invasive bladder cancer is a complete transurethral resection of the bladder tumor (TURBT). Intravesical chemotherapy is generally used as prophylactic or adjuvant therapy after complete endoscopic resection; it is rarely used as therapy to eradicate residual disease that could not be completely resected.


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