What follow-up is indicated in a healthcare worker who has been exposed to HIV?

Updated: Jul 27, 2020
  • Author: Ana Elizabeth Markelz, MD, FACP, FIDSA; Chief Editor: John Bartlett, MD  more...
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PEP is given for 28 days. If source person testing is negative for HIV, PEP can be stopped before 28 days. During the follow-up period, especially the first 6-12 weeks, exposed healthcare workers should undertake precautions to prevent further transmission of HIV. They should not donate blood, tissue, semen, or organs. They should not engage in sexual intercourse, become pregnant, or breastfeed. Follow-up HIV Ab testing should be performed at 6 weeks and 4 months. A negative result at 12 weeks reasonably excludes HIV infection related to the occupational exposure. Routine testing at 6 months postexposure is no longer recommended.

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