When is postexposure prophylaxis (PEP) indicated in occupational exposures to HIV?

Updated: Jul 27, 2020
  • Author: Ana Elizabeth Markelz, MD, FACP, FIDSA; Chief Editor: John Bartlett, MD  more...
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Answer

Answer

PEP is recommended when an exposure to an HIV-positive patient has occurred. PEP is generally not warranted in cases of unknown status, but this can be considered from a source with HIV risk factors. If the source person is unknown (sharps box injury), PEP is generally not warranted but can be considered when exposure to HIV-infected persons is likely.


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