What testing is indicated in a healthcare worker who has been exposed to HIV?

Updated: Jul 27, 2020
  • Author: Ana Elizabeth Markelz, MD, FACP, FIDSA; Chief Editor: John Bartlett, MD  more...
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For the healthcare worker, baseline laboratory studies include HIV, HCV Ab, HBV surface Ag, and HBV surface Ab. Hepatitis B testing depends on immunization status. Most healthcare personnel have been immunized against hepatitis B. If they know they responded to the vaccination series, they have lifelong immunity and require no further testing. If they are unaware of their response status, HBV surface Ab should be drawn to determine if they have a positive titer. If PEP is being considered and the healthcare worker is a female of childbearing age, an immediate pregnancy test should be performed. If HIV PEP is initiated, a baseline CBC count and renal and hepatic function should be assessed.

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