When should postexposure prophylaxis (PEP) be initiated after occupational exposure to HIV?

Updated: Jul 27, 2020
  • Author: Ana Elizabeth Markelz, MD, FACP, FIDSA; Chief Editor: John Bartlett, MD  more...
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When indicated, PEP should be initiated as soon as possible (ideally ≤2 hours and generally ≤72 hours) after exposure. The approach to PEP depends on the type of exposure, the source, and the HIV status of the source.

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