How is metaplastic breast cancer (MBC) differentiated from invasive ductal carcinoma?

Updated: May 24, 2018
  • Author: Peter Abdelmessieh, DO, MSc; Chief Editor: Marie Catherine Lee, MD, FACS  more...
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This diverse group of malignancies is identified as a single entity based on a similarity in clinical behavior. Compared with infiltrating ductal carcinoma, MBC tumors have the following characteristics:

  • Larger size
  • More rapid growth
  • Commonly node-negative
  • Typically ER negative, PR negative, and HER2 negative

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