Which pathological features have prognostic significance in ductal carcinoma in situ (DCIS)?

Updated: May 24, 2018
  • Author: Peter Abdelmessieh, DO, MSc; Chief Editor: Marie Catherine Lee, MD, FACS  more...
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Review of DCIS by a pathologist can identify prognostic features. Pathologists look at the following four distinct histologic features:

  • Tumor size
  • Necrosis presence
  • Nuclear grade
  • Width of surgical margin

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