How is endemic syphilis treated?

Updated: Sep 14, 2020
  • Author: Hassan I Galadari, MD; Chief Editor: Dirk M Elston, MD  more...
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Endemic syphilis responds well to penicillin and other treponemicidal drugs. Patients become noninfectious within 24 hours.

After successful treatment, the titer of nontreponemal tests shows a gradual decline and eventually becomes negative.

No vaccines for endemic syphilis are available.

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