How is endemic syphilis diagnosed?

Updated: Sep 14, 2020
  • Author: Hassan I Galadari, MD; Chief Editor: Dirk M Elston, MD  more...
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The best and most reliable method to diagnose endemic syphilis is to gather a thorough clinical history and to conduct a complete physical examination. Geographic data, including travel information, is invaluable in establishing the diagnosis.

Laboratory tests confirm the clinically based diagnosis. These laboratory tests are the same as those used for the diagnosis of venereal syphilis. [14]

Serologic, morphologic, and biochemical tests are not useful in distinguishing between the types of treponemal infections.

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