What is the role of percutaneous transluminal angioplasty and stenting (PTAS) in the treatment of transient ischemic attack (TIA)?

Updated: Dec 03, 2018
  • Author: Ashish Nanda, MD; Chief Editor: Andrew K Chang, MD, MS  more...
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Answer

A randomized trial has shown that aggressive medical management (antiplatelet therapy combined with intensive management of vascular risk factors) is safer than percutaneous transluminal angioplasty and stenting (PTAS) in patient with 70-99% stenosis of a major intracranial artery. Enrollment in this trial was stopped after 451 patients underwent randomization because the 30-day rate of stroke or death was 14.7% in the PTAS group and 5.8% in the medical-management group. [49]


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