What are the reported outcomes following modified radical mastectomy?

Updated: Jun 18, 2021
  • Author: Nafisa K Kuwajerwala, MD; Chief Editor: Erik D Schraga, MD  more...
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It currently remains the patient’s choice to undergo breast conservation or mastectomy with or without reconstruction. The European Organization for Research and Treatment of Cancer 10801 trial found no significant difference in the 20-year overall survival rate between women who underwent breast-conserving surgery and radiation and those who were treated with modified radical mastectomy, for stage 1 or 2 breast cancer. Overall survival at 20 years was 44% in the breast-conserving surgery group and 39% in the modified radical mastectomy group. Time to distant metastasis also did not differ significantly between the two groups, although the study did find that the 10-year locoregional recurrence of cancer was higher in the breast-conserving group than in the mastectomy patients (20% vs 12%, respectively). [7]

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