What is the role of medications in pediatric ECMO?

Updated: Dec 21, 2017
  • Author: Edwin Rodriguez-Cruz, MD; Chief Editor: Stuart Berger, MD  more...
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Answer

Answer

Aminocaproic acid may be required to reduce bleeding during surgery. Only minimal sedation with fentanyl, midazolam, or morphine is required after stabilization. Doses of most inotropic medications, such as dopamine, dobutamine, and epinephrine, can usually be decreased once the patient is on extracorporeal membrane oxygenation (ECMO).

Diuretics, such as furosemide (Lasix) and chlorothiazide (Diuril), may be required for mobilization of tissue fluids. Antacids and H2 antagonists are usually administered for GI tract bleeding. Phenobarbital can be used if the patient has seizures.

Antibiotics, such as ampicillin and cefotaxime, are used initially in the typical septicemic dosages; dosage modification may be needed, depending on the pathogen and sensitivity.

The duration of treatment will vary based on the initial diagnosis and the daily evaluation of the patient. It should be remembered that the longer the patient remains in this therapy, the more complications the patient may experience.


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