Which study is the criterion standard for the diagnosis of gastroesophageal reflux disease (GERD)?

Updated: Oct 16, 2020
  • Author: Marco G Patti, MD; Chief Editor: BS Anand, MD  more...
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Ambulatory 24-hour pH monitoring is the criterion standard in establishing a diagnosis of GERD, with a sensitivity of 96% and a specificity of 95%. It quantifies the gastroesophageal reflux and allows a correlation between the symptoms of reflux and the episodes of reflux.

Patients with endoscopically confirmed esophagitis do not need pH monitoring to establish a diagnosis of GERD.

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