What is the role of EGD in the diagnosis of gastroesophageal reflux disease (GERD)?

Updated: Oct 16, 2020
  • Author: Marco G Patti, MD; Chief Editor: BS Anand, MD  more...
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Esophagogastroduodenoscopy (EGD) demonstrates the anatomy and identifies the possible presence and severity of complications of reflux disease (esophagitis, Barrett esophagus, strictures). Using the patient's history and pathologic analysis of biopsy specimens obtained during endoscopy, the diagnosis of GERD can be made. EGD also excludes the presence of other diseases (eg, peptic ulcer) that can present similarly to GERD.

Although EGD is frequently performed to help diagnose GERD, it is not the most cost-effective diagnostic study, because esophagitis is present in only 50% of patients with GERD.

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