What were the results of the LOTUS trial on antireflux therapy for gastroesophageal reflux disease (GERD)?

Updated: Oct 16, 2020
  • Author: Marco G Patti, MD; Chief Editor: BS Anand, MD  more...
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The LOTUS trial—a 5-year, exploratory randomized, open, parallel-group trial—demonstrated that with antireflux therapy for GERD, either using drug-induced acid suppression with esomeprazole or laparoscopic antireflux surgery, most patients achieve remission and remain in remission at 5 years. [25]

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