Why does a high BMI contribute to gastroesophageal reflux disease (GERD)?

Updated: Oct 16, 2020
  • Author: Marco G Patti, MD; Chief Editor: BS Anand, MD  more...
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The mechanism by which a high BMI increases esophageal acid exposure is not completely understood. Increased intragastric pressure and gastroesophageal pressure gradient, incompetence of the lower esophageal sphincter (LES), and increased frequency of transient LES relaxations may all play a role in the pathophysiology of GERD in patients who are morbidly obese.

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