What are the complications of esophagitis?

Updated: May 28, 2020
  • Author: Deepika Devuni, MD; Chief Editor: BS Anand, MD  more...
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Various complications of esophagitis may be noted, including the following:

  • Bleeding and stricture formation
  • Barrett esophagus occurs when the normal squamous epithelium of the esophagus is replaced with columnar epithelium, and it is linked to the development of esophageal cancer; a systematic review of patients with Barrett esophagus also indicated a link between Barrett esophagus and colonic cancer (7.6% of patients with Barrett esophagus had colonic cancer vs 1.6% in controls) [2]
  • Perforation with mediastinitis, though rare, is a serious complication
  • Volume depletion and weight loss may occur secondary to the inability to swallow
  • Laryngitis, aspiration pneumonitis, and bronchospasm may occur if the gastric contents are refluxed up to the level of the larynx.
  • In infants, apnea and failure to thrive

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