What are the most common sites of clear cell renal cell carcinoma (CCRCC) metastasis?

Updated: Mar 11, 2019
  • Author: Ronald J Cohen, MB, BCh, PhD, FRCPA, FFPATH; Chief Editor: Liang Cheng, MD  more...
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Other studies have found spread of CCRCC along the inferior vena cava and/or renal vein in 22-24% of cases. [21, 24] Analysis of metastatic CCRCC deposits has shown the most commonly involved sites to be as follows [21, 25] :

  • Lung (33-72%)

  • Intra-abdominal lymph nodes (3-35%)

  • Bone (21-25%)

  • Brain (7-13%)

  • Liver (5-10%)

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