What are the genetic features characteristic of stromal tumors of uncertain malignant potential (STUMP)?

Updated: Jan 04, 2021
  • Author: Fabio R Tavora, MD, PhD; Chief Editor: Liang Cheng, MD  more...
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Answer

Answer

No information is available on genetic alterations of stromal tumors of uncertain malignant potential (STUMP).

A study by Pan et al was conducted to detect the chromosomal imbalances in stromal sarcoma and STUMP by using array comparative genomic hybridization (aCGH). The study found that stromal sarcoma and STUMP shared similar profiles of chromosomal imbalances (mainly deletions of chromosomes 13, 14, and 10). [25]


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