What are the European Society of Cardiology (ESC) treatment guidelines for neoplastic pericardial effusion without tamponade?

Updated: Apr 02, 2019
  • Author: Sean Spangler, MD; Chief Editor: Terrence X O'Brien, MD, MS, FACC  more...
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The ESC 2004 guideline and its 2015 update states that treatment of cardiac tamponade is a class I indication for pericardiocentesis in the presence of neoplastic pericarditis. [3, 32] In suspected neoplastic pericardial effusion without tamponade, the following are recommended: [32]

  • Systemic antineoplastic treatment as baseline therapy

  • Pericardiocentesis to relieve symptoms and to confirm diagnosis

  • Intrapericardial instillation of cytostatic/sclerosing agent

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