Which factors are associated with finding a specific etiology for acute pericarditis?

Updated: Apr 02, 2019
  • Author: Sean Spangler, MD; Chief Editor: Terrence X O'Brien, MD, MS, FACC  more...
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Given an overall lack of specificity of clinical features, diagnostic protocols to determine the etiology for pericarditis have been described. Following specific protocols, several investigators determined a specific etiology in 14-22% of patients. In one study, cardiac tamponade and an unfavorable clinical outcome, with persistence of fever, significant pericardial effusion, or general illness lasting longer than 1 week, was highly associated with finding a specific etiology. See an example under Workup.

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