What is HIV coinfection?

Updated: Apr 18, 2019
  • Author: R Chris Rathbun, PharmD, BCPS (AQ-ID), AAHIVP; Chief Editor: John Bartlett, MD  more...
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A significant amount of morbidity and mortality in persons with HIV infection results from coinfection with Mycobacterium tuberculosis (MTB), hepatitis B virus (HBV), or hepatitis C virus (HCV). Each of these infections is more difficult to manage in patients with HIV infection because of the accelerated rate of disease progression, drug-drug interactions, and additive toxicities that result from concomitant therapies.

The antiretroviral treatment sequencing strategy for each type of coinfection is challenging and must be tailored to individual patient-specific needs to provide the best possible outcome and to restore quality of life.

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